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Cayenne pepper extract is made from the chilli pepper Capsicum annuum, a member of the nightshade plant family. This pepper is famous for its somewhat hot and spicy flavour, which is attributed to the presence of capsaicin, a bioactive molecule. While research on the possible health benefits of cayenne peppers is limited, capsaicin, when taken as a supplement, has been linked to a variety of health benefits. These advantages include possible pain reduction, increased metabolism, and improved cardiovascular health. However, it’s crucial to remember that most existing research focuses on capsaicin as a solitary supplement, and further research including cayenne pepper is needed to investigate its possible health benefits.

a plant of cayenne pepper


Cayenne pepper extract is high in capsaicin, the chemical responsible for the spicy flavour of Capsicum annuum. Capsaicin and the numerous defensive plant components found in cayenne pepper extract are responsible for several potential health advantages. While some studies have been conducted, additional research is required to completely understand the degree of cayenne pepper’s impact on health. However, some of its potential health benefits are as follows:

  • Relieves pain: The pain-relieving benefits of cayenne pepper extract are mostly attributable to capsaicin, the chemical responsible for the pepper’s spiciness. Capsaicin is known to operate in the body by desensitising pain receptors. It can provide great relief from certain forms of pain when applied topically in the form of creams or patches, particularly in illnesses such as osteoarthritis, rheumatoid arthritis, and diabetic neuropathy. Capsaicin creams are supposed to function by depleting substance P, a neurotransmitter that delivers pain signals to the brain. Capsaicin lowers pain perception by diminishing substance P. Capsaicin-containing lotions for pain management are available over the counter, according to research, including a study published in the “Clinical Journal of Pain.”
  • High in antioxidant and anti-inflammatory: Cayenne pepper extract contains a variety of plant compounds that are protective, such as flavonoids, carotenoids, and vitamin C. These substances have potent antioxidant and anti-inflammatory activities. Antioxidants protect the body from oxidative stress, which is a balance of free radicals and antioxidants in the body that has been linked to a variety of chronic diseases. Regular consumption of antioxidant-rich foods, such as cayenne peppers, has been shown in studies to help maintain good health and increase the body’s antioxidant defences. According to a 2015 study, cayenne peppers exhibit high antioxidant activity. This antioxidant ability can help to lower the risk of cellular damage and inflammation, both of which are important for general health.
  • May benefit cardiovascular health: Capsaicin, the key ingredient in cayenne pepper extract, has anti-inflammatory effects that imply potential cardiovascular benefits. Chronic inflammation is a risk factor for a variety of heart disorders. Consumption of capsaicin-rich chilli peppers has been related to a lower risk of death from heart disease in studies. These findings, together with those of a 2019 Italian study including 22,811 adults, testify to capsaicin’s potential cardioprotective properties. While these findings are encouraging, maintaining a holistic, healthy lifestyle that includes a well-balanced diet and regular physical activity is critical for heart health.
heart health: benefits of grape seed extract & cayenne pepper

Incorporating cayenne pepper into your diet may improve flavour and maybe lessen the need for extra salt, though the effect of cayenne on taste perception and appetites has to be studied further. The findings show that cayenne pepper may have health advantages, but further human trials are needed to determine its full spectrum.


When cayenne pepper is consumed, it causes a number of reactions in the human body. Capsaicin is the primary active ingredient responsible for the actions of cayenne pepper. Capsaicin binds to specific receptors on sensory nerve endings in the mouth and gastrointestinal tract when consumed, primarily the transient receptor potential vanilloid 1 (TRPV1) receptor. This binding produces the heat and spiciness that cayenne peppers are famous for. Furthermore, capsaicin activates TRPV1 receptors, resulting in the production of neuropeptides such as substance P, which are involved in the transmission of pain signals to the brain. Capsaicin desensitises these receptors over time by repeatedly stimulating them, resulting in reduced pain sensitivity.

pain signals: cayenne pepper extract

Capsaicin may stimulate stomach acid production after entering the stomach, which can be both useful and potentially harmful. Increased stomach acid can help with digestion, but it might aggravate symptoms in people with disorders like gastroesophageal reflux disease (GERD). Capsaicin can alter the release of several digestive enzymes and increase the passage of food through the digestive system in the small intestine, potentially improving digestion. Capsaicin can also boost the release of endorphins, which are natural painkillers that provide a sense of well-being and happiness.

Capsaicin’s consumption on a regular basis may contribute to improved pain tolerance over time. Capsaicin activates a cascade of physiological responses by binding to TRPV1 receptors, resulting in the impression of spiciness, increased stomach acid secretion, improved digestion, and even the release of endorphins, making cayenne peppers a distinctive and flexible addition to one’s diet.


The correct amount of cayenne pepper extract depends on an individual’s tolerance and intended application. The research on the optimal dosage for cayenne pepper extract is rather limited, and it’s important to consider a variety of aspects, including an individual’s sensitivity to capsaicin (the main ingredient in cayenne peppers) and the goal of consumption.

In general, adding a pinch or a tiny amount of cayenne pepper to foods is harmless and adds a delightful level of spiciness. Dietary supplements containing cayenne pepper extract often provide precise recommended dosages for consumers seeking potential health benefits such as improved metabolism or digestive support. Depending on the product, these recommendations typically vary from 30 to 120 milligrams of cayenne pepper extract per day. However, because large doses can cause gastrointestinal discomfort in some people, it’s essential to start at the lower end of this range and gradually raise the dosage to determine tolerance.

It’s important to note that cayenne pepper extract may conflict with some medications or medical conditions, so talk to your doctor before using it. While studies suggests that cayenne pepper may have health benefits, it is important to visit a medical practitioner to identify the optimal dosage and ensure it meets with individual health needs. Moderation is essential with any supplement or dietary addition, and individuals should be mindful of their own responses to cayenne pepper extract to avoid adverse consequences.


Cayenne Pepper Extract is also available as:

  • Cayenne Capsicum Pepper Extract 0.5% Capsaicinoids (Chilli) (Capsicum annuum Cayenne) #
  • Cayenne Capsicum Pepper Extract 0.6% Capsaicinoids (Chilli) (Capsicum annuum Cayenne) #
  • Cayenne Capsicum Pepper Extract 4:1 (Chilli) (Capsicum annuum Cayenne) #
  • Cayenne Capsicum Pepper Extract 7:1 (Chilli) (Capsicum annuum Cayenne) #
  • Cayenne Capsicum Pepper Extract 8:1 (Chilli) (Capsicum annuum Cayenne) #
  • Cayenne Capsicum Pepper Powder (Chilli) (Capsicum annuum Cayenne) #
  • Cayenne Capsicum Pepper Powder (Chilli) (Capsicum annuum Cayenne) Heat Treated #
  • Cayenne Capsicum Pepper Powder 100K SHU (Chilli) (Capsicum annuum Cayenne) #
  • Cayenne Capsicum Pepper Powder 40K SHU (Chilli) (Capsicum annuum Cayenne) #

Cayenne Pepper Extract is commonly available in:

  • Cayenne Pepper Extract capsules
  • Cayenne Pepper powder extract
  • Cayenne Pepper liquid extract

Glentworth Formulations is here to suit your every need. Everything from Tablets, Capsules and Powder blends.

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