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Gynostemma extract is obtained from the Gynostemma pentaphyllum plant, which is a climbing vine native to China, Korea, and Japan. It’s a component of traditional Chinese medicine, and it’s been used for its possible health benefits. Gynostemma extract, also known as “Southern Ginseng” or “Jiaogulan,” includes bioactive components including as saponins (gypenosides), flavonoids, and polysaccharides, which are thought to contribute to its therapeutic benefits.

a photo of a plant called gynostemma extract

This extract is well-known for its adaptogenic properties, which help the body adapt to stress and promote overall well-being. It’s been linked to antioxidant, anti-inflammatory, and immune-boosting effects, making it a popular natural supplement in alternative medicine and wellness practises. Gynostemma extract is generally accessible in powders, capsules, and teas, with the goal of supporting energy, longevity, and many aspects of health and wellness.


Here are some potential benefits of Gynostemma extract:

  • Blood sugar management: According to research, Gynostemma extract may be beneficial in the management of diabetes, notably in enhancing insulin responsiveness and blood sugar control. In a study involving 16 people newly diagnosed with type 2 diabetes, those who consumed 6 grammes of Gynostemma tea per day for four weeks had a better insulin response than those who consumed green tea. Another trial, in which 25 people were given normal diabetic medication for four weeks before being randomly allocated to either 6 grams of Gynostemma tea or a green tea placebo for an additional eight weeks, found that the Gynostemma group had improved blood sugar control. This was demonstrated by lower haemoglobin A1C and fasting plasma glucose levels, demonstrating that this extract has the potential to improve insulin sensitivity and improve in blood sugar management for type 2 diabetes.
    a photo of blood sugar: benefit of gynostemma extract
  • May control obesity: Gynostemma extract has demonstrated promise in terms of influencing body composition and weight management. A study of 117 overweight people looked at the effects of a commercial Gynostemma extract. Those who took the this extract saw significant reductions in total body weight, body mass index (BMI), and total fat mass over the course of 16 weeks when compared to the placebo group. Notably, the study discovered gender disparities in fat loss. Individuals assigned male at birth had lower levels of visceral fat, specifically fat around the internal organs, while females had lower levels of gynoid fat, or fat around the hips, thighs, and breasts. These results indicate that Gynostemma extract may have a gender-specific effect on fat distribution and overall weight management.
  • May relieve stress and anxiety: This extract is well-known for its stress-relieving effects. In research of 72 people with a history of chronic stress and anxiety, participants who took an extract from Gynostemma leaves for eight weeks showed lower self-perceived stress levels than those who received a placebo. The study, however, found no significant variations in stress hormone levels (such as norepinephrine and cortisol) across the groups. Despite this, the self-reported reduction in stress levels among individuals who consumed This extract implies that it has the potential to be a natural stress-relieving agent, albeit the exact processes need to be researched further.

While these studies show promising results, it is important to note that research in this field is ongoing, and more extensive studies are required to fully understand the specific mechanisms of action as well as the broader effects of Gynostemma extract on diabetes, weight management, and stress relief. Individual responses to Gynostemma extract may also vary, therefore consulting a healthcare practitioner before incorporating it into a treatment programme is recommended, especially for people with pre-existing health concerns.


When Gynostemma extract is consumed, it activates a number of processes within the human body. The bioactive chemicals in this extract, including as gypenosides, flavonoids, and polysaccharides, pass through the gastrointestinal tract and are absorbed into the bloodstream. Once in the bloodstream, these compounds disseminate throughout the body, each performing a unique role in interacting with different cellular systems. The principal active agents, gypenosides, interact with cellular receptors and enzymes, perhaps altering insulin sensitivity, glucose metabolism, and fat breakdown. These interactions are thought to contribute to the claimed benefits of diabetes management and body weight regulation.

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Furthermore, these compounds are thought to influence stress response pathways. They may modulate stress-related hormone levels and neurotransmitter activity, which is consistent with Gynostemma extract’s documented stress-relieving benefits. Meanwhile, flavonoids, which have antioxidant and anti-inflammatory properties, and polysaccharides, which may alter immune function and gastrointestinal health, contribute to the overall physical benefits of Gynostemma extract. However, the precise mechanisms of action and specific pathways through which these compounds function within the body are still being researched. Understanding their absorption, metabolism, and distribution throughout the body remains a focus of scientific research in order to fully understand the effects of Gynostemma extract on human physiology.


Gynostemma extract, also known as Jiaogulan, has been tested in various doses for various health issues in research activities. For example, research on obesity used a daily dose of 450 mg for up to 16 weeks. Meanwhile, a study on its effects on chronic stress used a daily dose of 400 mg for eight weeks. In clinical trials, the daily dose was frequently divided into morning and evening administrations.

However, it is important to remember that the optimum dosage of Gynostemma extract may vary depending on a variety of circumstances, including an individual’s overall health, specific health condition, and the concentration of the extract. While studies can shed light on dosage levels utilised in research settings, finding the best and safest dosage for a person should be led by a healthcare expert. Depending on an individual’s response, tolerance, and any other current therapies or medication, the dosage may need to be adjusted. When considering the use of Gynostemma extract, it is critical to get the advice of a healthcare expert to identify the most appropriate and effective dosage for one’s specific health needs.


Gynostemma Extract is also available as:

  • Gynostemma Extract 98% Gypenosides (Southern Ginseng) (Gynostemma pentaphyllum)

Gynostemma Extract is commonly available in:

  • Gynostemma Extract capsules
  • Gynostemma powder extract
  • Gynostemma liquid extract

Glentworth Formulations is here to suit your every need. Everything from Tablets, Capsules and Powder blends.

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