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Berberine is a bioactive chemical that is derived from a variety of plants, including the Berberis shrub family. It belongs to a family of chemicals known as alkaloids. It is yellow and is often used as a dye. Berberine has a long history of usage in traditional Chinese medicine to treat a variety of diseases. Now, current study reveals that it supplies significant advantages for a variety of health issues.

Berberine plant  extract(yellow flowers)


Although berberine has many advantages and has been used for a long time, some of its advantages include:

  • May reduce blood sugar: Berberine has been found in studies to be effective as a diabetic therapy. According to research, it can improve blood sugar, fatty acids, and insulin levels. According to research, it improves the body’s response to insulin and protects your pancreas from producing more glucose.
  • May lower bad cholesterol: Elevated levels of LDL fatty acids and cholesterol may raise the risk of cardiovascular disease and stroke. Berberine may help decrease LDL cholesterol and triglyceride levels, according to some data. According to one review, berberine has cholesterol-lowering benefits in both animals and humans. It may help lower LDL, or “bad,” cholesterol while increasing HDL, or “good,” cholesterol. According to a review of the research, berberine together with lifestyle modifications is more effective than altering one’s habits alone in treating high cholesterol. Furthermore, hamster research discovered that berberine helps transfer extra cholesterol to the liver, where the body can process and drop it. As a result, total levels of triglycerides and cholesterol are reduced.
  • May help to lose weight: Although berberine is not a miracle weight-reduction medicine, it may help in weight loss in those with a body mass index (BMI) of over 30. Two trials have shown that using a berberine supplement for three months results in considerable weight reduction. This might be because berberine aids in the management of insulin and other hormones that influence the fat cells in human body. For instance, an investigation on the impact of berberine on weight loss published in Biomedicine & Pharmacotherapy in July 2020 discovered that berberine may help prevent obesity in a number of ways, including by altering the genetic factors that cause the human body to accumulate fat, preventing the growth of fat through stimulating enzymes that activate blood sugar and triglyceride uptake, and regulating gut hormones, which also affect weight and insulin resistance.
Biotin's one advantage of weight loss

It is often recommended to consult a medical practitioner or healthcare expert before introducing berberine as a supplement in your daily life. It can lead to serious health problems and severe health implications, if not supervised or prescribed.


Berberine was initially utilised for medicinal purposes more than 3000 years ago, when the barberry plant and its related species were grown in China and South Asia. The plant’s stems, leaves, and bark were utilised in a number of ways. Evidence also suggests that berberine-containing botanicals were used to cure various ailments in South America, the Middle East, and Europe.

Hundreds of researches on berberine have been conducted. The main way that berberine appears to work is by activating the enzyme adenosine monophosphate-activated protein kinase (AMPK). AMPK activation increases the absorption of glucose by cells, improving insulin sensitivity and lowering blood sugar levels. Additionally, berberine has been proven to activate AMPK and block the synthesis of inflammatory molecules, raising the likelihood that it might treat chronic inflammation-related disorders. Berberine also affects other substances within cells, perhaps affecting whether genes are activated or inactive. This may provide as protection against a number of chronic medical disorders.


There is no information or study on the amount of berberine that is effective or safe to take on a regular basis. Nonetheless, certain suggestions have been found in some research. Many of the trials listed in the article relied on daily doses ranging from 500 to 1,500 mg. It is considered normal to take 500 mg three times each day, for a total of 1,500 mg per day. However, no safe or effective amount of berberine has been found for kids. Before consuming berberine, see a healthcare expert if you have a medical condition or are taking any drugs. This is particularly important if you are presently taking diabetes medication.


Variations of Berberine include:

  • Berberine HCl 97% (Cortex Phellodendron chinensis)
  • Goldenseal (Hydrastis canadensis)
  • Oregon Grapes (Mahonia aquifolium)
  • Chinese Goldthread (Coptis chinensis)
  • Barberry Plants (Berberis)
  • Tree Turmeric (Berberis aristata)

Berberine extract is commonly available as:

  • Berberine extract tablets
  • Berberine extract capsules

Glentworth Formulations is here to suit your every need. Everything from Tablets, Capsules and Powder blends.

If you are wanting to know more information, please get in contact with us. Either using the contact form or contacting us directly on:

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