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Black seed extract is a traditional natural treatment that has been used for a long time in many civilizations, especially in the Middle East and Asia. It is made from the seeds of the Nigella sativa plant. These tiny, crescent-shaped seeds, often called black cumin or black caraway, have a strong perfume and a slightly bitter taste. Thymoquinone, one of the many bioactive components found in the extract, is thought to be the cause of many of its possible health benefits.

a bowl full of black seed extract

Because of its purported antioxidant, anti-inflammatory, and immune-boosting qualities, black seed extract is frequently taken as a dietary supplement or used as a herbal treatment. This makes it a topic of interest for a variety of health and wellness applications. It is noteworthy that although black seed extract has been traditionally used and has shown promise in research, additional research is necessary to completely comprehend its mechanisms of action and validate its prospective benefits for different medical conditions.


Black seed extract, which is derived from Nigella sativa seeds, has drawn interest since it may have a number of health benefits, some of which have been shown by studies. The following are some of the primary health benefits of black seed extract:

  • Immune System support: This extract has a reputation for strengthening the immune system. It has a number of compounds, including thymoquinone, which strengthens the immune system. Black seed has been shown in a study published in the “Journal of Ethnopharmacology” to promote bone marrow and immune cell formation, which enhances immunological function. This implies that it might aid in boosting the body’s defences against diseases and infections. It also has been shown in another study published in the “Iranian Journal of Immunology” to improve the function of natural killer cells, which are essential for recognising and destroying malignant or infectious cells. The extract’s rich phytochemical composition is thought to be responsible for its immune-modulating properties.
  • Anti Inflammatory properties: Chronic inflammation has been associated with a variety of health problems, including heart disease, arthritis, and cancer. There is potential for this extract to lessen inflammation. One of its key components, thymoquinone, has strong anti-inflammatory properties by preventing the release of substances that cause inflammation. A study that was published in “Oxidative Medicine and Cellular Longevity” emphasised black seed extract’s anti-inflammatory qualities. According to the study, it has the ability to lower inflammatory indicators, which suggests that it might be a useful natural treatment for illnesses when persistent inflammation is present.
  • Rich in Antioxidants: Antioxidants found in black seeds (black cumin) support the body fight oxidative stress. The ageing process and the emergence of chronic diseases are both linked to oxidative stress. The extract’s capacity to scavenge free radicals and shield cells from oxidative damage was shown in a study published in “Evidence-Based Complementary and Alternative Medicine”. Thymoquinone and thymohydroquinone are the two types of these antioxidants that support the extract’s protective properties against cells and tissues. Additionally, black seed may also help shield many systems and organs from oxidative damage. Its antioxidant qualities may be especially advantageous to the liver. Studies that were published in the “Journal of Biological Sciences” revealed that black seed can shield the liver from damage brought on by toxic substances and oxidative stress.
astragalus root extract benefits: immunity (black seed extract)

It’s crucial to remember that while though research on black seed extract’s possible health benefits is encouraging, further clinical trials are required to confirm its efficacy and determine the right dosages for various medical conditions. Before adding this extract to your regimen, like with any supplement, it’s best to consult a healthcare provider, particularly if you have underlying medical conditions or are taking medication.


This extract interacts with numerous biological processes and has a rich phytochemical content that contributes to its mechanism of action in the body. Thymoquinone, one of the active ingredients in black seed extract, is absorbed mostly through the gastrointestinal tract when consumed. Because thymoquinone is fat-soluble, it can be absorbed effectively when there are fats in the diet. These substances enter the bloodstream after absorption and travel to many organs and cells.

Black seed extract functions as an antioxidant, which is one of its primary modes of action. Compounds in the extract, including thymoquinone and thymohydroquinone, counteract dangerous free radicals that can put the body under oxidative stress. This antioxidant action aids in defending DNA and cellular structures from oxidative stress brought on by reactive oxygen species. Black seed extract improves cellular health overall and may help prevent chronic diseases linked to oxidative damage by lowering oxidative stress.

Additionally, via modulating different inflammatory pathways, black seed extract also possesses anti-inflammatory properties. In instance, it has been demonstrated that thymoquinone inhibits the release of compounds that promote inflammation. This anti-inflammatory effect can aid in the treatment of ailments including arthritis, cardiovascular disease, and other inflammatory disorders by lowering long-term inflammation in the body. The capacity of black seed extract to combat inflammation and oxidative stress is the main reason behind its beneficial effects, which enhance general health and wellbeing.


The correct dosage of black seed extract to take depends on a number of aspects, such as its intended use. Although black seed extract is generally thought to be safe when taken in accordance with suggested quantities, it’s important to adhere to recommendations and see a medical professional. Based on available research, a person should take 500 mg to 2,000 mg of black seed extract twice or three times a day.

Black seed extract is safe and effective within certain dosage limits, according to several research. For example, a study that was published in the “Journal of Ethnopharmacology” discovered that taking 1,000 mg of black seed extract daily was useful in easing rheumatoid arthritis symptoms without having a major negative impact. Furthermore, a study published in the “International Journal of Preventive Medicine” suggested that people with type 2 diabetes use 1,000–2,000 mg of black seed extract daily to help improve glycemic control.

It’s important to remember, though, that different people react differently to black seed extract, and that the correct dosage may depend on things like age, weight, and general health. For this reason, speaking with a medical professional is important when figuring out the right dosage for a given set of medical problems and goals. To guarantee safety and efficacy, it’s also advised to select premium, standardised black seed extract products and follow the dosage guidelines provided by the manufacturer.


Black Seed Extract is also available as:

  • Black Seed Extract 4:1 (Nigella sativa)
  • Black Seed Extract 6% Thymoquinone (Nigella sativa)
  • Black Seed Powder (Nigella sativa)

Black Seed Extract is commonly available in:

  • Black Seed Extract capsules
  • Black Seed powder extract
  • Black Seed liquid extract

Glentworth Formulations is here to suit your every need. Everything from Tablets, Capsules and Powder blends.

If you are wanting to know more information, please get in contact with us. Either using the contact form or contacting us directly on: enquiries@glentworthformulations.com.

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