Share this post:


Goldenseal extract is a botanical preparation derived from the goldenseal plant (Hydrastis canadensis), an eastern North American perennial herb. This extract is made from the plant’s roots and leaves, which have a long history of usage in traditional medicine for treating a variety of medical conditions, particularly those connected to infections and inflammation. In herbal medicine, goldenseal extract is highly appreciated and is often used in the form of teas, herbal extracts, or capsules to treat symptoms such as colds, hay fever, digestive problems, sore gums, and skin issues.

a photo depicting vibrant yellow flowers: goldenseal extract

Furthermore, it is commonly found in over-the-counter treatments such as ear drops, feminine hygiene products, eyewash solutions, cold and flu cures, allergy relief products, laxatives, and digestive aids. The principal alkaloid constituents in goldenseal extract are berberine, hydrastine, and canadine, which are thought to underpin its potential health benefits, notably in terms of antibacterial and anti-inflammatory qualities.


Here are some potential benefits of goldenseal extract:

  • May cure upper respiratory infections: The Hydrastis canadensis plant’s goldenseal extract has gained popularity as a natural remedy for upper respiratory tract infections, particularly the common cold. According to research, including cell and animal studies, one of its key active components, berberine, may have antibacterial and antiviral characteristics. These qualities are thought to support in the fight against illnesses produced by bacteria and viruses, including the viruses that cause the common cold. It is significant to remember, however, that the berberine concentrations utilised in this research frequently surpass what is found in ordinary goldenseal supplements, and the bioavailability of berberine from goldenseal may be lower. As a result, more research is needed to assess the effectiveness of goldenseal in treating upper respiratory tract infections in humans.
    a photo depicting lung infections: benefits of goldenseal extract
  • May prevent urinary tract infection: Goldenseal extract is also a popular herbal treatment for urinary tract infections (UTIs) and yeast infections. According to preliminary cell research, berberine, a key component of goldenseal, may be able to prevent certain bacteria and fungus from causing severe diseases. Berberine, for example, may reduce bacterial adhesion to bladder walls, potentially benefiting in the prevention and treatment of UTIs. Furthermore, berberine is thought to regulate the growth of Candida albicans, a fungus that, when overgrown, can cause yeast infections. According to certain studies, a combination of herbal extracts containing berberine may lower the occurrence of UTIs in humans. However, there have been few direct human studies on the usefulness of goldenseal in the treatment of UTIs and yeast infections, and further study is needed to establish its potential benefits.
  • May prevent STDs: Chlamydia and herpes are common sexually transmitted infections that can have serious consequences if not addressed. Earlier research suggested that berberine, the main active ingredient in goldenseal, could be utilised to treat chlamydia and herpes infections. These studies have proposed that chlamydia infections be treated with berberine-containing douches, vaginal suppositories, or oral goldenseal capsules. There is also some evidence that berberine-containing herbs, such as goldenseal, may help prevent herpes virus multiplication. However, the majority of these studies were conducted in the past, and there is no new research that substantially supports these conclusions. As a result, more recent research is required to determine the efficacy of goldenseal in treating chlamydia and herpes infections.

In conclusion, while goldenseal extract shows promise in a variety of health applications, including the treatment of upper respiratory infections, urinary tract infections, and certain sexually transmitted diseases, more research is needed to confirm its effectiveness and safety in human populations. Before utilising goldenseal or its extracts as a supplementary or alternative therapy for specific health conditions, users should contact with healthcare specialists.


When goldenseal extract is consumed, it begins to interact with the human body via its active ingredients, principally berberine. Berberine is absorbed in the gastrointestinal system upon oral administration and then reaches the bloodstream. Berberine can travel throughout the body once it enters the bloodstream, and its effects become more intense as it reaches specific target areas. Berberine has a wide-ranging effect on the body, with its methods of action linked to interactions with a variety of cellular processes and molecular pathways.

Berberine is known to have antibacterial properties by interfering with bacterial attachment to cell surfaces, making it potentially useful in the context of illnesses such as urinary tract infections (UTIs). It has also been demonstrated to alter cellular signalling pathways related to inflammation and oxidative damage. This suggests that berberine may assist in the regulation of the body’s inflammatory response and the reduction of oxidative damage. Berberine can also alter glucose metabolism and insulin sensitivity, which has led to its usage in blood sugar management.

blood sugar management: benefits of black garlic extract & banaba leaf extract & barley grass extract & bitter melon extract & ceylon cinnamon bark

The precise processes underlying these benefits are still being investigated, but it appears that berberine acts on various cellular targets, including enzymes, receptors, and gene expression, to produce therapeutic effects. Overall, the intricate interactions of berberine inside the human body allow goldenseal extract to possibly provide a variety of health advantages; however, additional research is required to completely clarify its mechanisms and validate its efficacy in various applications.


The ideal dosage of goldenseal extract for an individual can be difficult to determine because accessible forms and amounts vary significantly, and research on the optimal dosage is limited. Goldenseal supplements are available in a variety of formats, including capsules, tinctures, and teas, each with its own recommended dosage. Dried root supplements, for example, are generally taken in amounts ranging from 0.5 to 10 grams three times per day, whilst liquid extracts and tinctures are typically prescribed in doses ranging from 0.3 to 10 ml three times per day.

Goldenseal can also be prepared into a tea by steeping 2 teaspoons of dry herb in 1 cup of boiling water for about 15 minutes. It is important to note, however, that the optimal dosage for goldenseal is unknown due to a lack of significant study in this area.

Due to the lack of clear studies showing the most effective and safe dosages, it is essential to verify with a healthcare professional before utilising goldenseal extract or supplements. To select an adequate and safe dosage, individual factors such as age, overall health, and specific health issues should be considered. Individuals should also be cautious of potential interactions with other medication or medical conditions. Further research in this area is needed to provide more exact information on goldenseal dose for varied purposes.


Goldenseal Extract is also available as:

  • Goldenseal Extract 20:1 (Hydrastis canadensis)
  • Goldenseal Extract 4:1 (Hydrastis canadensis)
  • Goldenseal Extract 5% Alkaloids (Hydrastis canadensis)
  • Goldenseal Extract 5% Berberine (Hydrastis canadensis)
  • Goldenseal Leaf Powder (Hydrastis canadensis)
  • Goldenseal Root Powder (Hydrastis canadensis)

Goldenseal Extract is commonly available in:

  • Goldenseal Extract capsules
  • Goldenseal powder extract
  • Goldenseal liquid extract

Glentworth Formulations is here to suit your every need. Everything from Tablets, Capsules and Powder blends.

If you are wanting to know more information, please get in contact with us. Either using the contact form or contacting us directly on:

Share this post:

Subscribe to our monthly newsletter for Members Only intel!